APOA4 antibody (AA 239-371)

Catalog No. ABIN7859611

The Mouse Monoclonal anti-APOA4 antibody (Clone APOA4-3654) (ABIN7859611) specifically detects APOA4 in IHC. The antibody is reactive with Human samples.

Quick Overview for APOA4 antibody (AA 239-371) (ABIN7859611)

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: APOA4-3654

Product Details anti-APOA4 Antibody

Binding Specificity: AA 239-371

Purpose: Apolipoprotein A4 / apoA-IV Antibody

Specificity: Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant APOA4 protein fragment (around aa 239-371) (exact sequence is proprietary)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for APOA4

Target: APOA4 (Apolipoprotein A-IV (APOA4))

Alternative Name: Apolipoprotein A4

Background:

ApoA4, Apolipoprotein A-IV

Human ovarian cancer and cervical cancer tissues.

Molecular Weight: 46kDa

Gene ID: 337, 1247

UniProt: P06727

Pathways: Lipid Metabolism