GDF9 antibody (AA 250-450)

Catalog No. ABIN7859642

This Mouse Monoclonal antibody specifically detects GDF9 in IHC. It exhibits reactivity toward Human.

Quick Overview for GDF9 antibody (AA 250-450) (ABIN7859642)

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GDF9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: GDF9-6458

Product Details anti-GDF9 Antibody

Binding Specificity: AA 250-450

Purpose: GDF9 (Growth Differentiation Factor 9) Antibody

Specificity: GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/6458 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa250-450) of human GDF9 protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for GDF9

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Alternative Name: GDF9

Background:

Growth/differentiation factor 9, GDF-9, GDF9

Human ovary.

Molecular Weight: 51kDa

Gene ID: 2661, 25022

UniProt: O60383