Recombinant TUBB3 antibody (AA 250-450)

Catalog No. ABIN7859666

This Mouse Monoclonal antibody specifically detects TUBB3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant TUBB3 antibody (AA 250-450) (ABIN7859666)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RTUBB3-7406

Product Details anti-TUBB3 Antibody

Binding Specificity: AA 250-450

Purpose: Recombinant Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker) Antibody

Specificity: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. 79oΩIn adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa250-450) of human TUBB3 (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: Tubulin beta 3

Background:

beta 3 tubulin, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, TUBB3, TUBB4, Tubulin beta-3, Tubulin beta-4, Tubulin beta-III

Human brain or testis. PC3 cells.

Molecular Weight: 55kDa

Gene ID: 10381, 511743

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase