CD5L antibody (AA 269-366)

Catalog No. ABIN7863595

The Mouse Monoclonal anti-CD5L antibody is suitable to detect CD5L in samples from Human. It has been validated for IHC.

Quick Overview for CD5L antibody (AA 269-366) (ABIN7863595)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD5L antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CD5L-4420

Product Details anti-CD5L Antibody

Binding Specificity: AA 269-366

Purpose: CD5L / CD5LG / CD5 Ligand Antibody

Specificity: CD5L (CD5 Molecule-like), also known as API6, PRO229, Sp°™ or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L

Background:

AAC-11, AIM, API6, APOPTOSIS INHIBITOR 6, APOPTOSIS INHIBITOR OF MACROPHAGES, CD5 antigen like (scavenger receptor cysteine rich family), CD5 antigen-like, CT-2, Highly similar to ANTIGEN WC1.1 [Bos taurus], IgM-associated peptide, Pdp, PRO229, SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY, SP-alpha, Spalpha

293T, or MOLT-4 cells. Human tonsil or lymph node., Ramos

Molecular Weight: 38kDa

Gene ID: 922, 134035

UniProt: O43866