LRG1 antibody (AA 30-180)

Catalog No. ABIN7862634

The Mouse Monoclonal anti-LRG1 antibody is suitable to detect LRG1 in samples from Human. It has been validated for IHC.

Quick Overview for LRG1 antibody (AA 30-180) (ABIN7862634)

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRG1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: LRG1-4883

Product Details anti-LRG1 Antibody

Binding Specificity: AA 30-180

Purpose: LRG1 / Leucine Rich alpha-2-glycoprotein 1 Antibody

Specificity: LRG1 (leucine-rich °™2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 30-180) of human LRG1 protein (exact sequence is proprietary)

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Alternative Name: LRG1

Background:

A2GL, HMFT1766, Leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor

Human liver, pancreas or breast.

Molecular Weight: 38kDa

Gene ID: 116844, 655559

UniProt: P02750

Pathways: Brown Fat Cell Differentiation