Recombinant Keratin 75 antibody (AA 300-400)

Catalog No. ABIN7863724

The Mouse Monoclonal anti-Keratin 75 antibody is suitable to detect Keratin 75 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant Keratin 75 antibody (AA 300-400) (ABIN7863724)

Target: Keratin 75 (KRT75)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Keratin 75 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RKRTH-6617

Product Details anti-Keratin 75 Antibody

Binding Specificity: AA 300-400

Purpose: Recombinant Cytokeratin, Type II (Epithelial Marker) Antibody

Specificity: The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. It is usually used in a cytokeratin cocktail with type I cytokeratins antibody.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Synthetic peptide corresponding to Type II Cytokeratins residues within aa300-400 of Type II Cytokeratins

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Keratin 75

Target: Keratin 75 (KRT75)

Alternative Name: Cytokeratin, Type II

Background:

KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9

Skin or squamous cell carcinoma.

Molecular Weight: 66/65/64/57/62/60/51/54kDa

Gene ID: 51350, 654392

UniProt: Q01546