SSTR2 antibody (AA 300-500)

Catalog No. ABIN7859824

The Mouse Monoclonal anti-SSTR2 antibody (Clone SSTR2-7532) (ABIN7859824) specifically detects SSTR2 in IHC. The antibody is reactive with Human samples.

Quick Overview for SSTR2 antibody (AA 300-500) (ABIN7859824)

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SSTR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: SSTR2-7532

Product Details anti-SSTR2 Antibody

Binding Specificity: AA 300-500

Purpose: Somatostatin Receptor Type 2 (SSTR2) Antibody

Specificity: SSTRs (for somatostatin receptors) represent a family of G protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa300-500) of human SSTR2 (exact sequence is proprietary)

Isotype: IgG2b, lambda

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Alternative Name: Somatostatin Receptor Type 2

Background:

Somatostatin receptor type 2, SRIF-1, SRIF1, SS-2-R, SS2-R, SS2R, SST2, SSTR2

colon and liver.|Human Cerebrum and kidney. In lesser amounts in jejunum

Molecular Weight: 87/148 kDa

Gene ID: 6752, 514451

UniProt: P30874