PLA2R1 antibody (AA 300-600)

Catalog No. ABIN7859867

This Mouse Monoclonal antibody specifically detects PLA2R1 in IHC. It exhibits reactivity toward Human.

Quick Overview for PLA2R1 antibody (AA 300-600) (ABIN7859867)

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLA2R1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PLA2R1-4894

Product Details anti-PLA2R1 Antibody

Binding Specificity: AA 300-600

Purpose: PLA2R1 / Phospholipase A2 Receptor 1 Antibody

Specificity: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa300-600) of human PLA2R1 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PLA2R1

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Alternative Name: PLA2R1

Background:

PLA2R, PLA2-R, PLA2IR, CLEC13C, PLA2G1R

Human kidney.

Molecular Weight: 180kDa

Gene ID: 22925, 410477

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus