Recombinant PODXL antibody (AA 310-447)

Catalog No. ABIN7863251

This Mouse Monoclonal antibody specifically detects PODXL in ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant PODXL antibody (AA 310-447) (ABIN7863251)

Target: PODXL (Podocalyxin-Like (PODXL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: ELISA

Clone: RPODXL-2184

Product Details anti-PODXL Antibody

Binding Specificity: AA 310-447

Purpose: Recombinant Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Antibody

Specificity: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: Podocalyxin

Background:

PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1

HeLa, Raji or Jurkat cells. Human angiosarcoma or kidney tissue.

Molecular Weight: 165-170kDa

Gene ID: 5420, 732423

UniProt: O00592

Pathways: Tube Formation