MZF1 antibody (AA 37-128)

Catalog No. ABIN7864558

This Mouse Monoclonal antibody specifically detects MZF1 in IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for MZF1 antibody (AA 37-128) (ABIN7864558)

Target: MZF1 (Myeloid Zinc Finger 1 (MZF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MZF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-MZF1-1E8

Product Details anti-MZF1 Antibody

Binding Specificity: AA 37-128

Purpose: MZF1 (Transcriptional Corepressor) Antibody

Specificity: Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa37-128) of human MZF1 protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for MZF1

Target: MZF1 (Myeloid Zinc Finger 1 (MZF1))

Alternative Name: MZF1

Background:

Myeloid zinc finger 1, MZF 1, MZF-1, MZF1, MZF1_HUMAN, MZF1B, Zfp98, Zinc finger and SCAN domain containing protein 6, Zinc finger and SCAN domain-containing protein 6, Zinc finger protein 42, ZNF42, ZSCAN6

HeLa or U87 cells. Ubiquitous tissue expression.

Molecular Weight: 82.05kDa

Gene ID: 7593, 399810

UniProt: P28698