CD200R1 antibody (AA 50-250)

Catalog No. ABIN7865372

The Mouse Monoclonal anti-CD200R1 antibody is suitable to detect CD200R1 in samples from Human. It has been validated for WB.

Quick Overview for CD200R1 antibody (AA 50-250) (ABIN7865372)

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD200R1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: CD200R1-6493

Product Details anti-CD200R1 Antibody

Binding Specificity: AA 50-250

Purpose: CD200 Receptor 1 (CD200R1) / OX2 Antibody

Specificity: OX2 (CD200, MOX2), a member of the immunoglobulin superfamily (IgSF), is a 248 residue cell surface glycoprotein that is expressed in lymphoid cells, neurons and endothelium. OX2 receptor (OX2R) is a membrane protein with up to 70 % of its weight derived from N-linked glycosylation, it is primarily expressed in lymphoid and neuronal tissue. Phylogenetic analysis of OX2R with respect to other leukocyte IgSF glycoproteins suggests that OXR2 and OX2 share a common ancestral protein. The cytoplasmic portion of OX2R contains NPXY motifs that are known to interact with PTB/PID binding domains. The interaction between OX2 and OX2R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa50-250) of human CD200R1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD200R1

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Alternative Name: CD200 Receptor 1

Background:

CD200 cell surface glycoprotein receptor, MOX2 receptor, cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200

Human spleen, tonsil, lymph node or kidney. Daudi or U937 cells.

Molecular Weight: 39kDa

Gene ID: 131450

UniProt: Q8TD46