Elastase 3A antibody (AA 50-250)

Catalog No. ABIN7865399

The Mouse Monoclonal anti-Elastase 3A antibody is suitable to detect Elastase 3A in samples from Human. It has been validated for WB and IHC.

Quick Overview for Elastase 3A antibody (AA 50-250) (ABIN7865399)

Target: Elastase 3A (ELA3A)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Elastase 3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CELA3A-12552

Product Details anti-Elastase 3A Antibody

Binding Specificity: AA 50-250

Purpose: CELA3A / Chymotrypsin like elastase 3A Antibody

Specificity: Elastases belong to a subfamily of serine proteases that function to catalytically hydrolyze a wide variety of proteins. Elastase-3A, also known as ELA3A or ELA3, is a 270 amino acid protein that belongs to the elastase family and acts as an alanine-specific protease. Secreted as a zymogen from the pancreas, Elastase-3A functions as a digestive enzyme in the intestine that participates in metabolic degradation pathways by preferentially cleaving proteins that have alanine residues. In addition, Elastase-3A is thought to play a role in the metabolism and transport of cholesterol molecules in the intestine. Altered expression of Elastase-3A may be associated with pancreatic ductal carcinoma, a highly fatal cancer of the pancreatic ducts

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa50-250) of human CELA3A protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Elastase 3A

Target: Elastase 3A (ELA3A)

Alternative Name: CELA3A

Background:

ELA3, ELA3A

Human pancreas or pancreatic cancer.

Molecular Weight: 29 kDa

Gene ID: 10136

UniProt: P09093