CD48 antibody (AA 59-178)

Catalog No. ABIN7863662

This Mouse Monoclonal antibody specifically detects CD48 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for CD48 antibody (AA 59-178) (ABIN7863662)

Target: CD48

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD48 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CD48-4786

Product Details anti-CD48 Antibody

Binding Specificity: AA 59-178

Purpose: CD48 (Pan Leukocyte Marker) Antibody

Specificity: Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD48

Target: CD48

Alternative Name: CD48

Background:

B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2

Raji cells. Human lymph node or tonsil.

Molecular Weight: 45kDa

Gene ID: 962, 243564

UniProt: P09326