Recombinant CD48 antibody (AA 59-178)

Catalog No. ABIN7860414

The Rabbit Monoclonal anti-CD48 antibody is suitable to detect CD48 in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant CD48 antibody (AA 59-178) (ABIN7860414)

Target: CD48

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD48 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CD48-8602R

Product Details anti-CD48 Antibody

Binding Specificity: AA 59-178

Purpose: Recombinant CD48 (Pan Leukocyte Marker) Antibody

Specificity: Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CD48

Target: CD48

Alternative Name: CD48

Background:

B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2

Raji cells. Spleen, Human lymph node or tonsil.

Molecular Weight: 45kDa

Gene ID: 962, 243564