Recombinant CD31 antibody (AA 625-738)

Catalog No. ABIN7860534

The Mouse Monoclonal anti-CD31 antibody is suitable to detect CD31 in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant CD31 antibody (AA 625-738) (ABIN7860534)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD31 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RPECAM1-8829

Product Details anti-CD31 Antibody

Binding Specificity: AA 625-738

Purpose: Recombinant CD31 / PECAM-1 (Endothelial Cell Marker) Antibody

Specificity: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 625-738) of human CD31 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background:

EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA'

Jurkat cells. Tonsil or Angiosarcoma.|THP-1, Heart, Kidney, Spleen.

Molecular Weight: ~100kDa (endothelium) and ~130kDa (platelets)79oΩ

Gene ID: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization