Recombinant CALB1 antibody (AA 7-96)

Catalog No. ABIN7860581

This Mouse Monoclonal antibody specifically detects CALB1 in IHC and WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant CALB1 antibody (AA 7-96) (ABIN7860581)

Target: CALB1 (Calbindin (CALB1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: RCALB1-8499

Product Details anti-CALB1 Antibody

Binding Specificity: AA 7-96

Purpose: Recombinant Calbindin 1 (CALB1) Antibody

Specificity: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 é 79oΩ and é 79oΩ, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin é 79oΩ and Parvalbumin é 79oΩ (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 7-96) of human CALB1 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: Calbindin 1

Background:

avian-type, CAB27, CALB 1, CALB, CALB1, CALB1_HUMAN, Calbindin 1 28 kDa, Calbindin, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, RTVL H protein, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D-dependent calcium-binding protein

293T or HepG2 cells. Human prostate|kidney or liver.|lung|pancreas. Brain.

Molecular Weight: 52kDa

Gene ID: 793, 65425

UniProt: P05937