ZNF239 antibody (AA 83-233)
Quick Overview for ZNF239 antibody (AA 83-233) (ABIN7860641)
Target
See all ZNF239 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 83-233
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Purpose
- ZNF239 Antibody
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Specificity
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa83-233) of human ZNF239 protein (exact sequence is proprietary)
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- ZNF239 (Zinc Finger Protein 239 (ZNF239))
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Alternative Name
- ZNF239
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Background
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HOK-2, MOK2
HeLa or U87 cells. Human lymph node|pancreas|tonsil or testis.
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Molecular Weight
- 51.59kDa
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Gene ID
- 8187, 25040
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UniProt
- Q16600
Target
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