Recombinant Liver Arginase antibody (Arg1)

Catalog No. ABIN7863049

The Rabbit Monoclonal anti-Liver Arginase antibody (Clone ARG1-6790R) (ABIN7863049) specifically detects Liver Arginase in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Liver Arginase antibody (Arg1) (ABIN7863049)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ARG1-6790R

Product Details anti-Liver Arginase Antibody

Binding Specificity: AA 200-322, Arg1

Purpose: Recombinant Arginase 1 (Hepatocellular Carcinoma Marker) Antibody

Specificity: Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-322) of human ARG1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arginase 1

Background:

Arginase 1, ARG1, liver-type arginase, type I arginase

293T cells. Human liver or hepatocellular carcinoma (HCC).

Molecular Weight: 35-38kDa

Gene ID: 383, 440934

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin