Cadherin pan antibody (C-Term)

Catalog No. ABIN7860688

The Mouse Monoclonal anti-Cadherin pan antibody (Clone Pan-CAD-8020) (ABIN7860688) specifically detects Cadherin pan in IHC. The antibody is reactive with Human samples.

Quick Overview for Cadherin pan antibody (C-Term) (ABIN7860688)

Target: Cadherin pan (Cadherin Pan)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin pan antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: Pan-CAD-8020

Product Details anti-Cadherin pan Antibody

Binding Specificity: C-Term

Purpose: Pan-Cadherin Antibody

Specificity: Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as ≤-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin 6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human C-terminal of Pan-Cadherin (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Cadherin pan

Target: Cadherin pan (Cadherin Pan)

Alternative Name: Pan-Cadherin

Background:

Cadherin, CDH3, CDHP, 7B4 antigen, Cadherin-1, Cadherin-2, Cadherin-3, Cadherin-4, Cadherin-5, CAM 120/80, CD144, CD324, CD325, Cdh4, CDH5, CDHE, CDHN, E-cadherin, Epithelial cadherin, N-cadherin, NCAD, Neural cadherin, P-cadherin, Placental cadherin, UVO, Uvomorulin, Vascular endothelial cadherin

colon|Human heart|prostate or brain.

Molecular Weight: 120 kDa

Gene ID: 999, 1000, 1001

UniProt: P12830, P19022, P22223, P33151, P55283