Recombinant Actin, Muscle Specific antibody

Catalog No. ABIN7860845

This Mouse Monoclonal antibody specifically detects Actin, Muscle Specific in WB and IHC. It exhibits reactivity toward Human, Rabbit and Rat.

Quick Overview for Recombinant Actin, Muscle Specific antibody (ABIN7860845)

Target: Actin, Muscle Specific

Antibody Type: Recombinant Antibody

Reactivity: Human, Rabbit, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Actin, Muscle Specific antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RMSA-953

Product Details anti-Actin, Muscle Specific Antibody

Purpose: Recombinant Actin, Muscle Specific (Muscle Cell Marker) Antibody

Specificity: This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative.It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant protein corresponding to human muscle actin

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Actin, Muscle Specific

Target: Actin, Muscle Specific

Background:

ACTA, ACTA1, ACTA2, ACTC1, Actin, ACTSA, Alpha-2 actin, alpha skeletal muscle, Alpha-actin-1, Cardiac muscle alpha actin-1, Skeletal muscle alpha actin-1

Muscle or sarcoma. intestine or skeletal muscle.

Molecular Weight: 42kDa

Gene ID: 58, 59, 70

UniProt: P62736, P68032, P68133