BCL2L2 antibody

Catalog No. ABIN7863348

This Mouse Monoclonal antibody specifically detects BCL2L2 in IF and FACS. It exhibits reactivity toward Human.

Quick Overview for BCL2L2 antibody (ABIN7863348)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-BCL2L2-1A4

Product Details anti-BCL2L2 Antibody

Purpose: BCL2-like 2 (BCL2L2) / BCL-W Antibody

Specificity: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length BCL2L2 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: BCL2-like 2

Background:

BCL-W, BCL2-L-2, BCLW, KIAA0271, PPP1R51

HEK293, HePG2, MCF-7 or U87 cells., PC-3

Molecular Weight: 22-30kDa

Gene ID: 599, 410026

UniProt: Q92843