CA3 antibody

Catalog No. ABIN7864858

The Mouse Monoclonal anti-CA3 antibody is suitable to detect CA3 in samples from Human. It has been validated for IHC.

Quick Overview for CA3 antibody (ABIN7864858)

Target: CA3 (Carbonic Anhydrase III (CA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CA3-7884

Product Details anti-CA3 Antibody

Purpose: Carbonic Anhydrase 3 / CA3 Antibody

Specificity: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA III (carbonic anhydrase III), also known as Car3 or CA3, is a 260 amino acid cytoplasmic protein that is specifically expressed in muscle. Belonging to the a-carbonic anhydrase family, CA III is activated by proton donors such as imidazole and dipeptide histidylhistidine, and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human CA3 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CA3

Target: CA3 (Carbonic Anhydrase III (CA3))

Alternative Name: Carbonic Anhydrase 3

Background:

Apotransferrin, Beta-1 metal-binding globulin, Serotransferrin, Siderophilin, CA3, CA3QTL1, CA3

Muscle specific.

Molecular Weight: 28kDa

Gene ID: 761, 82129