CEBPZ antibody
Quick Overview for CEBPZ antibody (ABIN7864987)
Target
See all CEBPZ AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- CEBPZ Antibody
-
Specificity
- C/EBP (CCAAT/enhancer-binding protein ), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBP stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBP is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBP promoter may be involved with acute myeloid leukemia. The C/EBP gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2.
-
Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
Immunogen
- Protein domain of CEBPZ protein
-
Isotype
- IgG2c
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 200 μg/mL
-
Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C
-
Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Expiry Date
- 24 months
-
-
- CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))
-
Alternative Name
- CEBPZ
-
Background
-
CBF2, CTF2
Human skin or placenta. HeLa cells.
-
Molecular Weight
- 121kDa
-
Gene ID
- 10153, 135406
-
UniProt
- Q03701
Target
-