Recombinant D-Dimer antibody

Catalog No. ABIN7861194

The Rabbit Monoclonal anti-D-Dimer antibody is suitable to detect D-Dimer in samples from Human. It has been validated for WB.

Quick Overview for Recombinant D-Dimer antibody (ABIN7861194)

Target: D-Dimer

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This D-Dimer antibody is un-conjugated

Application: Western Blotting (WB)

Clone: FGG-13043R

Product Details anti-D-Dimer Antibody

Purpose: Recombinant D-Dimer / Fibrinogen gamma chain Antibody

Specificity: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a, b and g. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities and are mitogens for several cell types. This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human FGA protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for D-Dimer

Target: D-Dimer

Background:

fibrinogen, gamma polypeptide testicular tissue protein Li 70

HepG2 or A-549 cells. Human kidney.

Molecular Weight: 57kDa

Gene ID: 2266

UniProt: P02679