ERG antibody

Catalog No. ABIN7862751

This Mouse Monoclonal antibody specifically detects ERG in IHC. It exhibits reactivity toward Human.

Quick Overview for ERG antibody (ABIN7862751)

Target: ERG (ERG, ETS transcription factor (ERG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERG antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: ERG-2107

Product Details anti-ERG Antibody

Purpose: ERG / ETS Transcription Factor (Prostate Cancer Marker) Antibody

Specificity: The transcription factor erythroblastosis virus E26 transforming sequence related gene (ERG) functions as a regulator of key cellular functions to promote endothelial homeostasis.Expression of ERG has been observed in both benign and malignant vascular endothelial tumors, such as hemangiomas and Kaposi sarcomas, respectively.Carcinomas of the breast, colon, and urothelium have demonstrated absence of ERG expression, whereas presence of the protein has been confirmed in a subset of prostate carcinoma cases.Anti-ERG can be a useful tool for identifying vascular endothelial neoplasms and distinguishing prostate carcinoma from epithelial tumors of non-prostatic origin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length ERG protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ERG

Target: ERG (ERG, ETS transcription factor (ERG))

Alternative Name: ERG

Background:

ERG, ERG/EWS fusion gene, ERG/FUS fusion gene, ERG/TMPSSR2 fusion gene, ERG1, ETS-related, KCNH2, Oncogene ERG, p55, TMPRSS2/ERG fusion

Ewing sarcoma or prostate adenocarcinoma tissues., HUVEC cells. Human tonsil

Molecular Weight: 55kDa

Gene ID: 2078, 473819

UniProt: P11308