Recombinant FTL antibody

Catalog No. ABIN7862867

This Rabbit Monoclonal antibody specifically detects FTL in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant FTL antibody (ABIN7862867)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: FTL-3872R

Product Details anti-FTL Antibody

Purpose: Recombinant Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker) Antibody

Specificity: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human FTL protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: Ferritin, Light Chain

Background:

Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

HeLa or 293T cells. Human kidney, HePG2, liver or testis., Pancreas or Human Brain, Lung

Molecular Weight: 19-25kDa

Gene ID: 2512, 433670

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis