Recombinant FSHB antibody
Quick Overview for Recombinant FSHB antibody (ABIN7862863)
Target
See all FSHB AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Recombinant FSH-beta (Follicle Stimulating Hormone-beta) Antibody
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Specificity
- This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant hFSH beta sub-unit
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Isotype
- IgG, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
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Alternative Name
- FSH-beta
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Background
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Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta
Anterior Pituitary
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Molecular Weight
- 22kDa
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Gene ID
- 2488, 36975
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UniProt
- P01225
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
Target
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