Recombinant FOXL2 antibody

Catalog No. ABIN7863977

This Rabbit Monoclonal antibody specifically detects FOXL2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant FOXL2 antibody (ABIN7863977)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: FOXL2-8362R

Product Details anti-FOXL2 Antibody

Purpose: Recombinant FOXL2 Antibody

Specificity: FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human FOXL2 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background:

Blepharophimosis epicanthus inversus and ptosis 1, BPES 1, BPES, BPES1, Epicanthus inversus and ptosis 1, Forkhead box protein L2, Forkhead transcription factor FOXL2, PFRK, PINTO, PITUITARY FORKHEAD FACTOR, POF3

Nuclear expression in ovarian follicular and stromal cells. Granulosa cell tumor. K-562.

Molecular Weight: 38kDa

Gene ID: 668, 289292

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity