GTF2I antibody

Catalog No. ABIN7864754

This Mouse Monoclonal antibody specifically detects GTF2I in FACS. It exhibits reactivity toward Human.

Quick Overview for GTF2I antibody (ABIN7864754)

Target: GTF2I (General Transcription Factor III (GTF2I))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2I antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-GTF2I-1A7

Product Details anti-GTF2I Antibody

Purpose: GTF2I (General transcription factors IIi) Antibody

Specificity: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human GTF2I protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Alternative Name: GTF2I

Background:

BAP135, Bruton tyrosine kinase associated protein 135, BTK associated protein 135kD, BTKAP1, DIWS, FLJ38776, FLJ56355, General transcription factor II-I, GTFII-I, IB 291, IB291, SPIN, SRF Phox 1 interacting protein, TFII-I, Transcription factor II I, WBS, WBSCR6, Williams-Beuren syndrome chromosomal region 6 protein

HeLa or MCF-7 cells.

Molecular Weight: 112.42kDa

Gene ID: 2969, 647041