GCM2 antibody

Catalog No. ABIN7864587

The Mouse Monoclonal anti-GCM2 antibody (Clone PCRP-GCM2-1B3) (ABIN7864587) specifically detects GCM2 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for GCM2 antibody (ABIN7864587)

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GCM2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-GCM2-1B3

Product Details anti-GCM2 Antibody

Purpose: GCM2 Antibody

Specificity: Glial cells missing homolog 2 (GCM2), also known as Chorion-specific tran2scription factor GCMb, is a 506 amino acid nuclear protein. GCM2 is a tran2scription factor that acts as an essential regulator of parathyroid development. GCM2 is also thought to mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. GCM2 contains one N-terminal GCM domain, which has DNA binding activity. Mutations of the gene that encodes GCM2 are associated with hypoparathyroidism, an autosomal reces2sive condition characterized by hypocalcemia and hyperphosphatemia.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human GCM2 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Alternative Name: GCM2

Background:

hGCMb | GCMB

HeLa or MCF-7 cells.

Molecular Weight: 56.61kDa

Gene ID: 9247, 478588

UniProt: O75603