Recombinant CD235a/GYPA antibody

Catalog No. ABIN7861369

The Mouse Monoclonal anti-CD235a/GYPA antibody (Clone rGYPA-8948) (ABIN7861369) specifically detects CD235a/GYPA in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD235a/GYPA antibody (ABIN7861369)

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD235a/GYPA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RGYPA-8948

Product Details anti-CD235a/GYPA Antibody

Purpose: Recombinant Glycophorin A / CD235a (Erythrocyte Marker) Antibody

Specificity: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human glycophorin A protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CD235a/GYPA

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Alternative Name: Glycophorin A

Background:

Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha

K562 cells. Erythrocytes in any human tissues

Molecular Weight: 39kDa

Gene ID: 2993, 2994

UniProt: P02724

Pathways: Maintenance of Protein Location