GTF2IRD2 antibody

Catalog No. ABIN7861389

The Mouse Monoclonal anti-GTF2IRD2 antibody is suitable to detect GTF2IRD2 in samples from Human. It has been validated for WB and FACS.

Quick Overview for GTF2IRD2 antibody (ABIN7861389)

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2IRD2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-GTF2IRD2-1B12

Product Details anti-GTF2IRD2 Antibody

Purpose: GTF2IRD2 Antibody

Specificity: The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GTF2IRD2 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for GTF2IRD2

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Alternative Name: GTF2IRD2

Background:

FP630, GTF2IRD2A, GTF2IRD2 alpha

HeLa or K562 cells.

Molecular Weight: 107kDa

Gene ID: 84163, 647039

UniProt: Q86UP8