GCHFR antibody

Catalog No. ABIN7861392

The Mouse Monoclonal anti-GCHFR antibody is suitable to detect GCHFR in samples from Human. It has been validated for IHC.

Quick Overview for GCHFR antibody (ABIN7861392)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GCHFR antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: GCHFR-7731

Product Details anti-GCHFR Antibody

Purpose: GCHFR Antibody

Specificity: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment human GCHFR protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Alternative Name: GCHFR

Background:

GTP Cyclohydrolase I Feedback Regulatory Protein, GTP Cyclohydrolase I Feedback Regulator, GFRP, p35

Human liver or intestine.

Molecular Weight: 63kDa

Gene ID: 2644, 631717