GCHFR antibody

Catalog No. ABIN7864726

The Mouse Monoclonal anti-GCHFR antibody (Clone GCHFR-7732) (ABIN7864726) specifically detects GCHFR in IHC and WB. The antibody is reactive with Human samples.

Quick Overview for GCHFR antibody (ABIN7864726)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GCHFR antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: GCHFR-7732

Product Details anti-GCHFR Antibody

Purpose: GCHFR Antibody

Specificity: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment human GCHFR protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Alternative Name: GCHFR

Background:

GTP Cyclohydrolase I Feedback Regulatory Protein, GTP Cyclohydrolase I Feedback Regulator, GFRP, p35

Human liver or intestine.

Molecular Weight: 63kDa

Gene ID: 2644, 631717