HOMEZ antibody

Catalog No. ABIN7863302

This Mouse Monoclonal antibody specifically detects HOMEZ in FACS, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for HOMEZ antibody (ABIN7863302)

Target: HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HOMEZ antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: PCRP-HOMEZ-1A5

Product Details anti-HOMEZ Antibody

Purpose: Homeobox and Leucine Zipper Encoding / HOMEZ Antibody

Specificity: Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human HOMEZ protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for HOMEZ

Target: HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))

Alternative Name: Homeobox and Leucine Zipper Encoding

Background:

KIAA1443, Homeodomain leucine zipper-containing factor

Human testis, kidney or fetal lung.

Molecular Weight: 61.24kDa

Gene ID: 57594, 632332

UniProt: Q8IX15