Recombinant IMPAD1 antibody

Catalog No. ABIN7861500

The Rabbit Monoclonal anti-IMPAD1 antibody is suitable to detect IMPAD1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant IMPAD1 antibody (ABIN7861500)

Target: IMPAD1 (Inositol Monophosphatase Domain Containing 1 (IMPAD1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IMPAD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: IMP3-8934R

Product Details anti-IMPAD1 Antibody

Purpose: Recombinant IMP-3 Antibody

Specificity: Imp3, also known as BRMS2, C15orf12 or MRPS4, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human IMP3 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IMPAD1

Target: IMPAD1 (Inositol Monophosphatase Domain Containing 1 (IMPAD1))

Alternative Name: IMP-3

Background:

U3 Small Nucleolar Ribonucleoprotein Protein IMP3, BRMS2, MRPS4

HEK293T, MCF7, A549, K-562 , brain or lung.|Human liver

Molecular Weight: 22-70kDa

Gene ID: 55272, 513043

UniProt: Q9NV31

Pathways: Glycosaminoglycan Metabolic Process