Recombinant Cytokeratin 1 antibody

Catalog No. ABIN7861570

The Rabbit Monoclonal anti-Cytokeratin 1 antibody (Clone KRT1-8342R) (ABIN7861570) specifically detects Cytokeratin 1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Cytokeratin 1 antibody (ABIN7861570)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: KRT1-8342R

Product Details anti-Cytokeratin 1 Antibody

Purpose: Recombinant Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody

Specificity: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human KRT1 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: Cytokeratin 1

Background:

67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1

Human skin or cervix.

Molecular Weight: 67kDa

Gene ID: 38748, 80828