Keratin 3 antibody

Catalog No. ABIN7863050

The Mouse Monoclonal anti-Keratin 3 antibody (Clone KRT3-2542) (ABIN7863050) specifically detects Keratin 3 in WB and IHC. The antibody is reactive with Human, Rabbit and Cow samples.

Quick Overview for Keratin 3 antibody (ABIN7863050)

Target: Keratin 3 (KRT3)

Reactivity: Human, Rabbit, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Keratin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: KRT3-2542

Product Details anti-Keratin 3 Antibody

Purpose: Cytokeratin 3 (KRT3) (Corneal Epithelial Marker) Antibody

Specificity: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins, which are arranged in pairs of heterotypic keratin chains co-expressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy.KRT3/2542 recognizes the 64kD polypeptide/keratin K3 (cytokeratin 3) of rabbit corneal epithelium and keratin K76 (cytokeratin K2p) of palate epithelium. As such represents an excellent marker for studying corneal epithelial-type differentiation. Also recognizes bovine snout and lip epithelium, as well as a rabbit corneal cell line.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Tissue, cells or virus corresponding to Rabbit Cytokeratin 3/CK-3. Rabbit corneal epithelial keratin.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Keratin 3

Target: Keratin 3 (KRT3)

Alternative Name: Cytokeratin 3

Background:

65 KDa Cytokeratin, CK3, CK-3, cytokeratin-3, Keratin, keratin 3, Keratin, Type II Cytoskeletal 3, Keratin-3, Type II Cytoskeletal 3, Type-II keratin Kb3

A431 cells. Human cornea.

Molecular Weight: 65kDa

Gene ID: 38550, 680652

UniProt: P12035