Cytokeratin 5 antibody

Catalog No. ABIN7861593

The Mouse Monoclonal anti-Cytokeratin 5 antibody is suitable to detect Cytokeratin 5 in samples from Human. It has been validated for IHC.

Quick Overview for Cytokeratin 5 antibody (ABIN7861593)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: KRT5-6-2090

Product Details anti-Cytokeratin 5 Antibody

Purpose: Cytokeratin 5/6 (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody

Specificity: It recognizes polypeptides of 58 kDa and 56 kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human KRT5 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Alternative Name: Cytokeratin 5

Background:

CK5, Keratin-5, KRT5, Cytoskeletal 6A, KRT6A

HeLa, HepG2 or PC12 cells. Human prostate, tonsil or skin.

Molecular Weight: 58kDa (KRT5), 56kDa (KRT6A)

Gene ID: 3852, 3853, 433845

UniProt: P13647, P02538