Mammaglobin antibody

Catalog No. ABIN7861680

The Mouse Monoclonal anti-Mammaglobin antibody is suitable to detect Mammaglobin in samples from Human. It has been validated for IHC and WB.

Quick Overview for Mammaglobin antibody (ABIN7861680)

Target: Mammaglobin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mammaglobin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: MGB-2704

Product Details anti-Mammaglobin Antibody

Purpose: Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody

Specificity: Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human SCGB2A2 (Mammaglobin-1) protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Mammaglobin

Target: Mammaglobin

Background:

Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2

HeLa or MCF-7 cells. Mammary gland specific. Overexpressed in breast cancer. Skin.

Molecular Weight: 18kDa

Gene ID: 4250, 46452

UniProt: Q13296