Recombinant TIMP2 antibody

Catalog No. ABIN7863833

The Rabbit Monoclonal anti-TIMP2 antibody (Clone TIMP2-8193R) (ABIN7863833) specifically detects TIMP2 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant TIMP2 antibody (ABIN7863833)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: TIMP2-8193R

Product Details anti-TIMP2 Antibody

Purpose: Recombinant TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody

Specificity: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human TIMP2 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2

Background:

Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2

Normal Placenta|Prostate or Ovarian Carcinoma.

Molecular Weight: 21kDa

Gene ID: 7077, 633514

UniProt: P16035

Pathways: cAMP Metabolic Process