MEF2D antibody

Catalog No. ABIN7863121

The Mouse Monoclonal anti-MEF2D antibody (Clone PCRP-MEF2D-3A4) (ABIN7863121) specifically detects MEF2D in IHC, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for MEF2D antibody (ABIN7863121)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2D antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-MEF2D-3A4

Product Details anti-MEF2D Antibody

Purpose: MEF2D / Myocyte enhancer factor 2D (Transcription Factor) Antibody

Specificity: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human MEF2D protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D

Background:

MADS box transcription factor 2 polypeptide D, Myocyte specific enhancer factor 2, polypeptide D

HeLa cells.

Molecular Weight: 55.94kDa

Gene ID: 4209, 314327

UniProt: Q14814