MYH7 antibody

Catalog No. ABIN7861807

The Mouse Monoclonal anti-MYH7 antibody (Clone MYH7-727) (ABIN7861807) specifically detects MYH7 in IHC. The antibody is reactive with Human samples.

Quick Overview for MYH7 antibody (ABIN7861807)

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MYH7-727

Product Details anti-MYH7 Antibody

Purpose: MYH7 Antibody

Specificity: Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis, vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8), three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1), and MHC-≤/slow (MYH7 or MHC-≤), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes hypertrophic cardiomyopathy.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human MYH7 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: MYH7

Background:

Beta myosin heavy chain, cardiac muscle beta isoform, CMD1S, CMH1, MPD1, MyHC-beta, MyHC-slow, MYHCB, Myopathy, distal 1, Myosin heavy chain (AA 1-96), Myosin heavy chain slow isoform, Myosin heavy chain, cardiac muscle beta isoform, Myosin, heavy chain 7, cardiac muscle, beta, Myosin, heavy polypeptide 7, cardiac muscle, beta, Myosin-7, Rhabdomyosarcoma antigen MU RMS 40.7A, SPMD, SPMM

Skeletal muscle.

Molecular Weight: 223kDa

Gene ID: 4625, 719946

UniProt: P12883