Recombinant PHOX2B antibody

Catalog No. ABIN7863572

The Rabbit Monoclonal anti-PHOX2B antibody (Clone PHOX2B-7161R) (ABIN7863572) specifically detects PHOX2B in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant PHOX2B antibody (ABIN7863572)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PHOX2B-7161R

Product Details anti-PHOX2B Antibody

Purpose: Recombinant PHOX2B Antibody

Specificity: Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system.PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human PHOX2B protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background:

NBLST2, NBPhox, Neuroblastoma paired type homeobox protein, Neuroblastoma Phox, Paired like homeobox 2b, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B, PHOX2B homeodomain protein, PMX2B

brain and adrenal gland., Expressed in neuroblastoma

Molecular Weight: 32kDa

Gene ID: 8929, 87202

UniProt: Q99453