POGZ antibody

Catalog No. ABIN7864446

The Mouse Monoclonal anti-POGZ antibody (Clone PCRP-POGZ-1B2) (ABIN7864446) specifically detects POGZ in FACS. The antibody is reactive with Human samples.

Quick Overview for POGZ antibody (ABIN7864446)

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POGZ antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-POGZ-1B2

Product Details anti-POGZ Antibody

Purpose: POGZ Antibody

Specificity: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human POGZ protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for POGZ

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Alternative Name: POGZ

Background:

KIAA0461, ZNF280E, ZNF635m, Pogo transposable element with ZNF domain

HeLa or U87 cells. Human placenta|tonsil or colon.

Molecular Weight: 155.3kDa

Gene ID: 23126, 25040

UniProt: Q7Z3K3