PCGF3 antibody

Catalog No. ABIN7861936

The Mouse Monoclonal anti-PCGF3 antibody (Clone PCRP-PCGF3-1D5) (ABIN7861936) specifically detects PCGF3 in IHC, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for PCGF3 antibody (ABIN7861936)

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PCGF3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-PCGF3-1D5

Product Details anti-PCGF3 Antibody

Purpose: PCGF3 Antibody

Specificity: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human PCGF3 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for PCGF3

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Alternative Name: PCGF3

Background:

DONG1, PCGF3, PCGF3_HUMAN, Polycomb group ring finger 3, Polycomb group RING finger protein 3, Ring finger protein 3, RING finger protein 3A, RNF3A

HeLa or MCF-7 cells. Human brain|testis or smooth muscle.

Molecular Weight: 28.12Da

Gene ID: 10336, 731755

UniProt: Q3KNV8

Pathways: Chromatin Binding