KCNJ6 antibody

Catalog No. ABIN7864234

The Mouse Monoclonal anti-KCNJ6 antibody (Clone KCNJ6-7557) (ABIN7864234) specifically detects KCNJ6 in IHC. The antibody is reactive with Human samples.

Quick Overview for KCNJ6 antibody (ABIN7864234)

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNJ6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: KCNJ6-7557

Product Details anti-KCNJ6 Antibody

Purpose: GIRK2 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody

Specificity: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human KCNJ6 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for KCNJ6

Target: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Alternative Name: GIRK2

Background:

inwardly rectifying subfamily J member 6, BIR1, G protein activated inward rectifier potassium channel 2, GIRK2, hiGIRK2, Inward rectifier K(+) channel Kir3.2, Inward rectifier potassium channel KIR3.2, KATP2, KCNJ6, Kcnj7, KIR3.2, KPLBS, Potassium inwardly rectifying channel subfamily J member 6, Potassium voltage gated channel subfamily J member 6

Human brain or pancreas.

Molecular Weight: 48kDa

Gene ID: 3763, 626242