PRMT7 antibody

Catalog No. ABIN7863261

The Mouse Monoclonal anti-PRMT7 antibody (Clone PCRP-PRMT7-1A7) (ABIN7863261) specifically detects PRMT7 in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for PRMT7 antibody (ABIN7863261)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRMT7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-PRMT7-1A7

Product Details anti-PRMT7 Antibody

Purpose: PRMT7 Antibody

Specificity: Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human PRMT7 protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7

Background:

[Myelin basic protein]-arginine N-methyltransferase PRMT7, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7

HeLa, MCF7 or HepG2 cells.

Molecular Weight: 78.46kDa

Gene ID: 54496, 640229

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization