Retinoid X Receptor gamma antibody

Catalog No. ABIN7862011

The Mouse Monoclonal anti-Retinoid X Receptor gamma antibody (Clone PCRP-RXRG-5C9) (ABIN7862011) specifically detects Retinoid X Receptor gamma in FACS. The antibody is reactive with Human samples.

Quick Overview for Retinoid X Receptor gamma antibody (ABIN7862011)

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor gamma antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-RXRG-5C9

Product Details anti-Retinoid X Receptor gamma Antibody

Purpose: RXRG Antibody

Specificity: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human RXRG protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Alternative Name: RXRG

Background:

NR2B3, Nuclear receptor subfamily 2 group B member 3, Retanoic X receptor gamma, Retinoic acid receptor RXR gamma, Retinoid X receptor gamma, RXR gamma, RXRC, Rxrg

HeLa or MCF-7 cells.

Molecular Weight: 50-54kDa

Gene ID: 6258, 26550

UniProt: P78347

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway