S100A11 antibody

Catalog No. ABIN7864492

This Mouse Monoclonal antibody specifically detects S100A11 in IHC. It exhibits reactivity toward Human.

Quick Overview for S100A11 antibody (ABIN7864492)

Target: S100A11 (S100 Calcium Binding Protein A11 (S100A11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A11 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: S100A11-7394

Product Details anti-S100A11 Antibody

Purpose: S100A11 (S100 calcium binding protein A11) / Calgizzarin Antibody

Specificity: Calgizzarin is a Ca2+-binding protein of the S100 family. The proteins comprising the S-100 protein family have two EF-hand structures per molecule of protein. Expression of these family members occurs primarily in neurons or retinal photoreceptor cells, and may also be involved in a wide variety of cellular functions including cell growth, cell-cell communication, energy metabolism and intracellular signal transduction. They have also been linked to various pathologies, including Alzheimer s disease, schizophrenia and cancer. Calgizzarin is highly expressed in lung tissue and is also expressed in kidney, liver, brain, heart and smooth muscle. It is an important androgen-responsive protein produced by Sertoli cells and might play a role in spermatogenesis regulation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human S100A11 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for S100A11

Target: S100A11 (S100 Calcium Binding Protein A11 (S100A11))

Alternative Name: S100A11

Background:

Epididymis secretory protein Li 43, HEL S 43, Metastatic lymph node gene 70 (MLN70) protein, Protein S100-A11, N-terminally processed, Protein S100-C, Protein S100A11, Protein S100C, S100 calcium binding protein A11, S100a11, S100C

Human ovarian carcinoma or thyroid carcinoma.

Molecular Weight: 11kDa

Gene ID: 6282, 417004

UniProt: P31949

Pathways: S100 Proteins